The whole cascade converges into the phosphorylation of the AChR subunits and rapsyn; rapsyn is a structural protein that self-aggregates providing a scaffold that anchors AChRs with the actin cytoskeletonthrough the mediation of microtubule actin cross-linking factor 1 (MACF1)to form the mature clusters (Borges and Ferns,2001; Lee et al
The whole cascade converges into the phosphorylation of the AChR subunits and rapsyn; rapsyn is a structural protein that self-aggregates providing a scaffold that anchors AChRs with the actin cytoskeletonthrough the mediation of microtubule actin cross-linking factor 1 (MACF1)to form the mature clusters (Borges and Ferns,2001; Lee et al.,2009; Zuber and Unwin,2013; Oury et al.,2019;…