Blue edges represent novel ppi
Blue edges represent novel ppi. MAP1CL3C and SH3GLB1. Strikingly, reduction of IRGM expression using small interfering RNA impairs both Measles computer virus (MeV), Hepatitis C computer virus (HCV) and human immunodeficiency computer virus-1 (HIV-1)-induced autophagy and viral particle production. Moreover we found that the expression of IRGM-interacting MeV-C, HCV-NS3 or HIV-NEF proteinsper seis sufficient to…