1B)
1B). of GBM patients, suggesting that an increased abundance of the EGFR may also be responsible for tumorigenesis in primary GBM (7, 19). Interestingly, somatic mutations within the EGFR kinase domain name, which are frequently identified in non-small cell lung cancer, have only rarely been identified in GBM (8, 14, 20). Given that abnormal regulation…