Often, POCTs are not held to the same standards as of regular laboratory diagnostic assessments or assays. are very important for accurate diagnosis, surveillance, control and management of animal diseases. This review addresses the different D-Pantothenate Sodium types of POCTs currently available for companion and food animal disease diagnostics, assessments in the pipeline and their advantages and disadvantages. Keywords: point-of-care, veterinary, animal, disease, diagnostics Introduction Point-of-care testing (POCT) is defined by International Standard ISO 22870 as testing that is performed near or at the site of a patient with the result leading to possible change in the care of the patient. The test is performed outside of a diagnostic laboratory near the patient with a rapid turnaround time. This enables rapid decision making and faster care or treatment of the patient. The POCT has been called by many names in human testing such as patient focused testing, near patient testing, near or next to the patient testing, and bedside testing in humans. In animal diagnostics, the POCT has been called as pen-side, animal-side, farm-side, barn-side or flock-side testing. Literature on POCT began in 1984 with self-monitored blood glucose assessments to monitor diabetes in people. As of August 1, 2022, there are 23,802 hits when you search for point-of-care test on Google search engine. This review is focused on POCT for animal infectious diseases. The keywords used for literature search were point-of-care test/testing, POCT, animal disease, veterinary, contamination/infectious, pathogen, and diagnosis. A point-of-care testing can be done in a number of places or areas. In human medicine, this could be the patient’s home, clinic or health care provider’s office, emergency care, or in a public place such as an airport or conference center. In the case of animal health, this could be the farm or flock side or pet’s home, a veterinary hospital or a veterinarian’s office or a common place. Around the human side, there are a number of POCT currently available to test for electrolytes, blood gases, cholesterol, cardiac enzymes such as troponin, abuse of drugs such as barbiturates or benzodiazepines, and various infectious brokers TSPAN7 or their antibody response. Regulatory oversight and quality control (a well-organized quality assurance program) are crucial components for the reliability and sustainability of POCTs whether these assessments are used for surveillance, outbreak, regulatory or recovery testing (1). There are a number of ways by which POCT can be classified such as based on analytes tested, technologies and methodologies used (2). In this review classification of assessments based on three analytes, i.e., antigen, antibody and nucleic acid is discussed. Per a 2022 BioSpace Report D-Pantothenate Sodium (3), Veterinary POCT market was valued at around D-Pantothenate Sodium $2.15 billion in 2020. It is estimated to grow at a 12.3% rate from 2021 to 2030 and projected to be worth $5.69 billion by 2030 (3). This rapid growth is usually augmented by evolving technology and increasing market need to respond to new and emerging diseases including the ongoing COVID-19 pandemic. In veterinary diagnostics, the companion animal market is more D-Pantothenate Sodium receptive to new POCTs even if they are expensive since cost is not a primary deciding factor here compared to food animal industry (4). Antigen based assays Antigen and antibody based POCT are immunoassays that are available for testing many animal diseases and for animal health monitoring. The most widely used immunoassay configuration is the enzyme-linked immunosorbent assay (ELISA) as they are easy to develop, easy to use and easy to validate compared to nucleic acid based assays (5). However, their specificity and sensitivity are often inferior to nucleic acid-based assays. Lateral flow assays are commonly used in POCT as an easy-to-use method to read results by the end users, especially for those who are not technology-savvy. There are several advantages to lateral flow assays including relative easiness to manufacture, scalability, simple to use, easy to read the results, suitable to use in any environment and D-Pantothenate Sodium for any applications whether in veterinary.